The Global Polio Laboratory Network Management System support the annual reporting and accreditation assessments of laboratories

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 Global Polio Laboratory Network Management System (GPLNMS)

Effective polio surveillance requires virologists, epidemiologists, doctors and national immunization programme staff, backed up by a global network of laboratories.
The Global Polio Laboratory Network (GPLN) was established in 1990 by WHO and national governments. Its primary responsibility is to distinguish polio as a cause of acute flaccid paralysis (AFP) from diseases other than poliomyelitis.
The GPLN consists of 145 laboratories in a three-tiered structure.

  • National laboratories: national laboratories follow standardized procedures for detecting polioviruses from stool samples collected from AFP cases.
  • Regional reference laboratories: regional reference labs confirm whether any polioviruses detected are wild or may have originated from the oral polio vaccine (i.e. are vaccine-derived polioviruses).
  • Global specialized laboratories: all wild polioviruses detected are referred to one of the seven specialized global laboratories to monitor virus transmission patterns.

All laboratories are continually monitored for their adherence to quality indicators and have annual accreditation assessments.

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